Human ABCC10 Matched Antibody Pair set for ELISA use
Capture Antibody: Rabbit purified polyclonal anti-ABCC10
Detection Antibody: Mouse purified polyclonal anti-ABCC10
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Antigen Detail | |
|---|---|
| Target | ABCC10 |
| Description | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Polyclonal |
| Host Species | Mouse |
| Conjugation | Unconjugated |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human ABCC10 Matched Antibody Pair set for ELISA use Capture Antibody: Rabbit purified polyclonal anti-ABCC10 Detection Antibody: Mouse purified polyclonal anti-ABCC10 |
| Specificity | Validated for detecting natural and recombinant human ABCC10 |
| Research Area | Multi-drug resistance |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | ABCC10 |
| Full Name | Multidrug resistance-associated protein 7 |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | ABCC10; EST182763; MRP7; SIMRP7; ATP binding cassette subfamily C member 10 |
| Gene ID | 89845 |
| Uniprot ID | Q5T3U5 |
| GeneCards | ABCC10 |
| HGNC | 52 |
| Ensembl | ENSG00000124574 |
| OMIM | 612509 |
| Involvement in Disease | Diseases associated with ABCC10 include Borna Disease and Abcd Syndrome. |
| Function | ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. |
| Related Pathways | Its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Imipramine/Desipramine Pathway, Pharmacokinetics. |
For Research Use Only.