Human BCAP31 Matched Antibody Pair set for ELISA use
Capture Antibody: Mouse monoclonal anti-BCAP31
Detection Antibody: Rabbit purified polyclonal anti-BCAP31
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Antigen Detail | |
|---|---|
| Target | BCAP31 |
| Description | B-cell receptor-associated protein 31 is a protein that in humans is encoded by the BCAP31 gene. BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis. BCAP31 drives TNBC development by modulating ligand-independent EGFR trafficking and spontaneous EGFR phosphorylation. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Mouse |
| Clone | IV01547 |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Polyclonal |
| Host Species | Rabbit |
| Conjugation | Unconjugated |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human BCAP31 Matched Antibody Pair set for ELISA use Capture Antibody: Mouse monoclonal anti-BCAP31 Detection Antibody: Rabbit purified polyclonal anti-BCAP31 |
| Specificity | Validated for detecting natural and recombinant human BCAP31 |
| Research Area | Apoptosis |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | BCAP31 |
| Full Name | B Cell Receptor Associated Protein 31 |
| Alternative Names | BCR-Associated Protein Bap31 |
| Gene ID | 10134 |
| Uniprot ID | P51572 |
| GeneCards | BCAP31 |
| HGNC | 16695 |
| Ensembl | ENSG00000185825 |
| OMIM | 300398 |
| Involvement in Disease | Diseases associated with BCAP31 include Deafness, Dystonia, And Cerebral Hypomyelination and Adrenoleukodystrophy. |
| Function | Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis. |
| Related Pathways | Its related pathways are AKT Siganaling Pathway and p70S6K Signaling. |
For Research Use Only.