Human DCTD Matched Antibody Pair set for ELISA useCapture Antibody: Rabbit purified polyclonal anti-DCTDDetection Antibody: Mouse polyclonal anti-DCTD
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Antigen Detail | |
|---|---|
| Target | DCTD |
| Description | dCMP deaminase is an enzyme which converts deoxycytidylic acid to deoxyuridylic acid. It plays an important role in the regulation of the pool of deoxynucleotides in higher organisms. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Polyclonal |
| Host Species | Mouse |
| Conjugation | Unconjugated |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human DCTD Matched Antibody Pair set for ELISA use Capture Antibody: Rabbit purified polyclonal anti-DCTD Detection Antibody: Mouse polyclonal anti-DCTD |
| Specificity | Validated for detecting natural and recombinant human DCTD |
| Research Area | Chromatin Modifying |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | DCTD |
| Full Name | DCMP Deaminase |
| Background | The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | Deoxycytidylate Deaminase |
| Gene ID | 1635 |
| Uniprot ID | P32321 |
| HGNC | 2710 |
| Ensembl | ENSG00000129187 |
| OMIM | 607638 |
| Involvement in Disease | Diseases associated with DCTD include Glass Syndrome and Granulomatosis With Polyangiitis. |
| Function | Supplies the nucleotide substrate for thymidylate synthetase. |
| Related Pathways | Its related pathways are Metabolism and Metabolism of nucleotides. |
For Research Use Only.
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