Human EMAP-II Matched Antibody Pair Set [ABP-P-219] (CAT#: ABP-P-219)

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The antibody pair set can be used to detect Human EMAP-II by sandwich ELISA. This antigen affinity purified capture antibody, combined with biotinylated detection antibody, allows for the detection of recombinant EMAP-II.

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Antigen Detail
TargetEMAP-II
DescriptionThe protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
Species ReactivityHuman

Capture Antibody
Capture ClonalityPolyclonal
Host SpeciesGoat
ProductionAntiserum
IsotypeIgG
PurificationAffinity Chromatography
BufferA sterile filtered antibody solution was lyophilized from PBS, pH 7.2.
ApplicationELISA

Detection Antibody
Det-ClonalityPolyclonal
Host SpeciesGoat
ProductionAntiserum
ConjugationBiotin
IsotypeIgG
PurificationAffinity Chromatography
ApplicationA sterile filtered antibody solution was lyophilized from PBS, pH 7.2.

General Product Property
Product OverviewThe antibody pair set can be used to detect Human EMAP-II by sandwich ELISA. This antigen affinity purified capture antibody, combined with biotinylated detection antibody, allows for the detection of recombinant EMAP-II.
SpecificityBoth the capture and the detection antibodies in this set react with Human EMAP-II.
Research AreaImmunology
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLiquid
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Plasma; Cell Culture Supernatant
Usage StatementAntibody is for research use only and not for use in diagnostic or therapeutic procedures.

Target Overview
Gene SymbolEMAP-II
Full Nameaminoacyl tRNA synthetase complex-interacting multifunctional protein 1
BackgroundThe protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
Alternative NamesEndothelial monocyte-activating polypeptide II; Multisynthase complex auxiliary component p43; Small inducible cytokine subfamily E member 1; EMAPII; EMAP-2; EMAP-II; SCYE1; EMAP2; p43; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; HLD3
Gene ID9255(Human)
Uniprot IDQ12904(Human)

For Research Use Only.

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