Name: Human F13B ELISA Matched Antibody Pair Set [ABP-Q-04-156]
SKU: ABP-Q-04-156
Price: 1120 USD

Human F13B ELISA Matched Antibody Pair Set [ABP-Q-04-156] (CAT#: ABP-Q-04-156)

Product Quick View

Human F13B antibody pair set for ELISA useCapture Antibody: rabbit anti-Human F13B monoclonal antibodyDetection Antibody: rabbit anti-Human F13B polyclonal antibody conjugated to HRP

(Note: Please select the requirements to fit you project. If you have any other requirements, please specify. If no specific requirements, you don't need to select any button.)

Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$1,120.00
Antibody Pair Set-Package 2	15 × 96 tests	$2,331.43

Datasheet

MSDS

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

Antigen Detail
Target	F13B
Description	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Factor XIII acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Defects in F13B are the cause of factor XIII subunit B deficiency ( FA13BD ) which is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Rabbit
Clone	IV01377
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Polyclonal
Host Species	Rabbit
Conjugation	HRP
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human F13B antibody pair set for ELISA use Capture Antibody: rabbit anti-Human F13B monoclonal antibody Detection Antibody: rabbit anti-Human F13B polyclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human F13B
Range	6.25-400 pg/mL
Research Area	Serum Proteins
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	F13B
Full Name	Coagulation Factor XIII B Chain
Background	This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.
Alternative Names	FXIIIB
Gene ID	2165
Uniprot ID	P05160

For Research Use Only.

Human F13B ELISA Matched Antibody Pair Set [ABP-Q-04-156] (CAT#: ABP-Q-04-156)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview