Human GBP2 Matched Antibody Pair set for ELISA use
Capture Antibody: Rabbit purified polyclonal anti-GC
Detection Antibody: Mouse purified polyclonal anti-GC
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Antigen Detail | |
|---|---|
| Target | GC |
| Description | Vitamin D-binding protein (DBP), also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene. The Gc protein has important physiological functions that include involvement in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5a for neutrophils in inflammation and macrophage activation. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Polyclonal |
| Host Species | Mouse |
| Conjugation | Unconjugated |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human GBP2 Matched Antibody Pair set for ELISA use Capture Antibody: Rabbit purified polyclonal anti-GC Detection Antibody: Mouse purified polyclonal anti-GC |
| Specificity | Validated for detecting natural and recombinant human GC |
| Research Area | Human Protein |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | GC |
| Full Name | GC Vitamin D Binding Protein |
| Background | The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] |
| Alternative Names | DBP-Maf |
| Gene ID | 2638 |
| Uniprot ID | P02774 |
| HGNC | 4187 |
| Ensembl | ENSG00000145321 |
| OMIM | 139200 |
| Involvement in Disease | Diseases associated with GC include Rickets and Blastomycosis. |
| Function | Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. |
| Related Pathways | Its related pathways are Vitamin D Metabolism and Metabolism of fat-soluble vitamins. |
For Research Use Only.