Human IFNA5 antibody pair set for ELISA useCapture Antibody: rabbit anti-Human IFNA5 monoclonal antibodyDetection Antibody: rabbit anti-Human IFNA5 polyclonal antibody conjugated to HRP
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Antigen Detail | |
|---|---|
| Target | IFNA5 |
| Description | Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone | IV01668 |
| Purification | Affinity Chromatography |
| Buffer | Prior to lyophilization: PBS, pH 7.4 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Polyclonal |
| Host Species | Rabbit |
| Conjugation | HRP |
| Purification | Affinity Chromatography |
| Buffer | Prior to lyophilization: PBS, containing 50 % HRP-Protector |
General Product Property | |
|---|---|
| Product Overview | Human IFNA5 antibody pair set for ELISA use Capture Antibody: rabbit anti-Human IFNA5 monoclonal antibody Detection Antibody: rabbit anti-Human IFNA5 polyclonal antibody conjugated to HRP |
| Specificity | Quantitative determination of Human IFNA5 |
| Range | 39.06-2500 pg/mL |
| Research Area | Innate Immunity |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | IFNA5 |
| Full Name | Interferon Alpha 5 |
| Background | IFNA5 (Interferon Alpha 5) is a Protein Coding gene. Diseases associated with IFNA5 include Hemangioma Of Lung. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Measles. Gene Ontology (GO) annotations related to this gene include cytokine activity and type I interferon receptor binding. |
| Alternative Names | IFN-Alpha-5 |
| Gene ID | 3442 |
| Uniprot ID | P01569 |
For Research Use Only.
Application