Name: Human IL-32 ELISA Matched Antibody Pair Set [ABP-Q-04-237]
SKU: ABP-Q-04-237
Price: 919.6 USD

Human IL-32 ELISA Matched Antibody Pair Set [ABP-Q-04-237] (CAT#: ABP-Q-04-237)

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Human IL-32 antibody pair set for ELISA useCapture Antibody: rabbit anti-IL32A monoclonal antibodyDetection Antibody: rabbit anti-IL32A monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	IL-32
Description	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Rabbit
Clone	IV01822
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Rabbit
Conjugation	HRP
Clone	RD10449
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human IL-32 antibody pair set for ELISA use Capture Antibody: rabbit anti-IL32A monoclonal antibody Detection Antibody: rabbit anti-IL32A monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human SP-10
Range	23.44-1500 pg/mL
Research Area	Innate Immunity; Adaptive Immunity
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	IL32
Full Name	Interleukin 32
Background	This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alternative Names	TAIFb; IL-32beta
Gene ID	9235
Uniprot ID	9235

For Research Use Only.

Human IL-32 ELISA Matched Antibody Pair Set [ABP-Q-04-237] (CAT#: ABP-Q-04-237)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview