Human IL-7 ELISA Matched Antibody Pair Set [ABP-Q-04-247] (CAT#: ABP-Q-04-247)

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Human IL-7 antibody pair set for ELISA useCapture Antibody: mouse anti-IL-7 monoclonal antibodyDetection Antibody: rabbit anti-Human IL7 polyclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $919.60
Antibody Pair Set-Package 2 15 × 96 tests $1,919.66
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Lot Number

Antigen Detail

TargetIL-7
DescriptionIL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRβ) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.
Species ReactivityHuman

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesMouse
CloneIV01966
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody

Det-ClonalityPolyclonal
Host SpeciesRabbit
ConjugationHRP
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property

Product OverviewHuman IL-7 antibody pair set for ELISA use
Capture Antibody: mouse anti-IL-7 monoclonal antibody
Detection Antibody: rabbit anti-Human IL7 polyclonal antibody conjugated to HRP
SpecificityQuantitative determination of Human IL7
Range3.91-250 pg/mL
Research AreaInnate Immunity
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolIL7
Full Nameinterleukin 7
BackgroundThe protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Alternative NamesIL-7; Interleukin-7
Gene ID3574
Uniprot IDP13232

For Research Use Only.

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