Human KLK3 Matched Antibody Pair Set [ABP-S-052933] (CAT#: ABP-S-052933)

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Anti-PSA Antibody Pair Set Capture Antibody: Mouse Monoclonal Detection Antibody: Mouse Monoclonal IgG2a-Unconjugated

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Lot Number

Antigen Detail

TargetPSA
Species ReactivityHuman

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesMouse
ImmunogenPSA antibody was raised in mouse using human PSA antigen purified from seminal plasma as the immunogen.
CloneIV01296
IsotypeIgG2a
PurificationAffinity Chromatography
BufferPBS, pH 7.4, containing 0.1% Proclin 300
ApplicationELISA

Detection Antibody

Det-ClonalityMonoclonal
Host SpeciesMouse
ImmunogenPSA antibody was raised in mouse using human PSA antigen purified from seminal plasma as the immunogen.
ConjugationUnconjugated
CloneRD10376
IsotypeIgG2a
PurificationProtein A
ApplicationPBS, pH 7.4, 0.1 % NaN3.

General Product Property

Product OverviewAnti-PSA Antibody Pair Set
Capture Antibody: Mouse Monoclonal
Detection Antibody: Mouse Monoclonal IgG2a-Unconjugated
SpecificityThe specificity of capture antibody: Human PSA antibody
The specificity of detection antibody: Specific for PSA
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLiquid
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 set
Sample TypeSerum; Plasma; Cell Culture Supernatant
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolKLK3
Full Namegamma-seminoprotein or kallikrein-3
BackgroundProstate-specific antigen (PSA), also known as γ-cysteine protein or kallikrein 3 (KLK3), is a glycoprotease encoded by the KLK3 gene in humans. PSA is a member of the kallikrein-related peptidase family and is secreted by epithelial cells of the prostate gland.

PSA is produced for ejaculation, it liquefies the semen in the semen and allows the sperm to swim freely. It is also believed to help dissolve cervical mucus and allow sperm to enter the uterus.

PSA is present in small amounts in the serum of healthy prostate patients, but is usually elevated in the presence of prostate cancer or other prostate diseases. PSA is not a unique indicator of prostate cancer, but it can also detect prostatitis or benign prostatic hyperplasia.
Alternative NamesKLK3; APS; KLK2A1; PSA; hK3; kallikrein related peptidase 3; Prostate Specific Antigen
Uniprot IDP01374

For Research Use Only.

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