Human Lipoprotein A antibody pair set for sandwich ELISA useCapture Antibody: Monoclonal IgGDetection Antibody: Biotin-Rabbit Monoclonal IgG
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Antigen Detail | |
|---|---|
| Target | Lipoprotein A |
| Description | Lipoprotein(a) is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological studies have identified lipoprotein(a) as a risk factor for atherosclerosis and related diseases, such as coronary heart disease and stroke. Lipoprotein(a) was discovered in 1963 by Kåre Berg.[6] The human gene encoding apolipoprotein(a) was successfully cloned in 1987. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone | IV01763 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Rabbit |
| Immunogen | Recombinant Human LipoProtein A Protein. |
| Conjugation | Biotin |
| Clone | RD1040 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human Lipoprotein A antibody pair set for sandwich ELISA use Capture Antibody: Monoclonal IgG Detection Antibody: Biotin-Rabbit Monoclonal IgG |
| Specificity | Both the capture and the detection antibodies in this set react with Human Lipoprotein A . |
| Sensitivity | 1890 pg/mL |
| Range | 15.625ng/ml-1000ng/ml |
| Research Area | Cardiovascular; Immunology; Signal Transduction |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | LPA |
| Full Name | Lipoprotein A |
| Background | Lipoprotein(a) is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological studies have identified lipoprotein(a) as a risk factor for atherosclerosis and related diseases, such as coronary heart disease and stroke. Lipoprotein(a) was discovered in 1963 by Kåre Berg.[6] The human gene encoding apolipoprotein(a) was successfully cloned in 1987. |
| Alternative Names | LPA; AK38; APOA; LP; Lipoprotein(a); Lp(a) |
| Gene ID | 4018 |
| Uniprot ID | P08519 |
| GeneCards | LPA |
| HGNC | 6667 |
| Ensembl | ENSG00000198670 |
| OMIM | 152200 |
| Involvement in Disease | Diseases associated with LPA include Lipoprotein Quantitative Trait Locus and Familial Hyperlipidemia. |
| Function | Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330. |
| Related Pathways | Its related pathways are Lipoprotein metabolism and amb2 Integrin signaling. |
For Research Use Only.
Application
