Name: Human M-CSF ELISA Matched Antibody Pair Set [ABP-Q-04-119]
SKU: ABP-Q-04-119
Price: 919.6 USD

Human M-CSF ELISA Matched Antibody Pair Set [ABP-Q-04-119] (CAT#: ABP-Q-04-119)

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Human M-CSF antibody pair set for ELISA useCapture Antibody: rabbit anti-M-CSF monoclonal antibodyDetection Antibody: rabbit anti-M-CSF monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	M-CSF
Description	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Rabbit
Clone	IV0112
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Rabbit
Conjugation	HRP
Clone	RD10243
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human M-CSF antibody pair set for ELISA use Capture Antibody: rabbit anti-M-CSF monoclonal antibody Detection Antibody: rabbit anti-M-CSF monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human M-CSF
Range	23.44-1500 pg/mL
Research Area	Innate Immunity
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	CSF1
Full Name	colony stimulating factor 1 (macrophage)
Background	The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.
Alternative Names	Macrophage colony-stimulating factor 1; CSF-1; Lanimostim; M-CSF; MCSF
Gene ID	1435
Uniprot ID	P09603

For Research Use Only.

Human M-CSF ELISA Matched Antibody Pair Set [ABP-Q-04-119] (CAT#: ABP-Q-04-119)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview