Human OSM Matched Antibody Pair Set [ABP-S-02133] (CAT#: ABP-S-02133)

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Human OSM antibody pair set for sandwich ELISA useCapture Antibody: Monoclonal IgGDetection Antibody: Biotin-Rabbit Monoclonal IgG

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,392.00
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Lot Number

Antigen Detail

TargetOSM
DescriptionOncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells.
Species ReactivityHuman

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesRabbit
CloneIV01893
IsotypeIgG
PurificationAffinity Chromatography
BufferPBS, pH 7.4, containing 0.1% Proclin 300
ApplicationELISA

Detection Antibody

Det-ClonalityMonoclonal
Host SpeciesRabbit
ImmunogenRecombinant Human OSM Protein.
ConjugationBiotin
CloneRD1014
IsotypeIgG
PurificationAffinity Chromatography
BufferPBS, pH 7.4

General Product Property

Product OverviewHuman OSM antibody pair set for sandwich ELISA use
Capture Antibody: Monoclonal IgG
Detection Antibody: Biotin-Rabbit Monoclonal IgG
SpecificityBoth the capture and the detection antibodies in this set react with Human OSM.
Sensitivity2.3 pg/mL
Range7.8 pg/mL-500 pg/mL
Research AreaCardiovascular; Immunology; Signal Transduction
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLiquid
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypePlasma; Serum; Cell Culture Supernatant
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolOSM
Full Nameoncostatin M
BackgroundOncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells.
Alternative NamesPP10187; Cerebral cavernous malformations 2 protein; Malcavernin; OSM; C7orf22
GeneCardsOSM
HGNC8506
EnsemblENSG00000099985
OMIM165095
Involvement in DiseaseDiseases associated with OSM include Plasmacytoma and Cerebral Meningioma.
FunctionGrowth regulator. Inhibit the proliferation of many tumor cell lines. Stimulate the proliferation of AIDS cells. It regulates the production of cytokines, including IL-6, G-CSF and GM-CSF in endothelial cells. Type I OSM receptor (heterodimer composed of LIFR and IL6ST) and type II OSM receptor (heterodimer composed of OSMR and IL6ST) are used. Participate in the maturation of fetal liver cells, thereby promoting liver development and regeneration (through similarity).

For Research Use Only.

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