Human RELT ELISA Matched Antibody Pair Set [ABP-Q-04-319] (CAT#: ABP-Q-04-319)

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Human RELT antibody pair set for ELISA useCapture Antibody: rabbit anti-Human RELT / TNFRSF19L monoclonal antibodyDetection Antibody: rabbit anti-Human RELT / TNFRSF19L monoclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
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Lot Number

Antigen Detail

TargetRELT
DescriptionReceptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. RELT/TNFRSF19L is a type I transmembrane glycoprotein with a cysteine-rich extracellular domain, possessing significant homology to other members of the TNFR superfamily, especially TNFRSF19, DR3, OX40, and LTbeta receptor. RELT/TNFRSF19L is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. RELT/TNFRSF19L is able to activate the NF-κB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. Although the soluble form of RELT fusion protein does not inhibit the one-way mixed lymphocyte reaction, immobilized RELT/TNFRSF19L is capable of costimulating T-cell proliferation in the presence of CD3 signaling.
Species ReactivityHuman

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesRabbit
CloneIV01257
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody

Det-ClonalityMonoclonal
Host SpeciesRabbit
ConjugationHRP
CloneRD10130
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property

Product OverviewHuman RELT antibody pair set for ELISA use
Capture Antibody: rabbit anti-Human RELT / TNFRSF19L monoclonal antibody
Detection Antibody: rabbit anti-Human RELT / TNFRSF19L monoclonal antibody conjugated to HRP
SpecificityQuantitative determination of Human RELT
Range39.06-2500 pg/mL
Research AreaImmune response
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolRELT
Full NameRELT TNF Receptor
BackgroundThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Alternative NamesRELT Tumor Necrosis Factor Receptor; AI3C
Gene ID84957
Uniprot IDQ969Z4

For Research Use Only.

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