Name: Human SLAMF6 ELISA Matched Antibody Pair Set [ABP-Q-04-340]
SKU: ABP-Q-04-340
Price: 1120 USD

Human SLAMF6 ELISA Matched Antibody Pair Set [ABP-Q-04-340] (CAT#: ABP-Q-04-340)

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Human SLAMF6 antibody pair set for ELISA useCapture Antibody: mouse anti-SLAMF6 monoclonal antibodyDetection Antibody: rabbit anti-SLAMF6 monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$1,120.00
Antibody Pair Set-Package 2	15 × 96 tests	$2,331.43

Datasheet

MSDS

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Lot Number

Antigen Detail
Target	SLAMF6
Description	SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Mouse
Clone	IV01230
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Rabbit
Conjugation	HRP
Clone	RD10180
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human SLAMF6 antibody pair set for ELISA use Capture Antibody: mouse anti-SLAMF6 monoclonal antibody Detection Antibody: rabbit anti-SLAMF6 monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human SLAMF6
Range	7.03-450 pg/mL
Research Area	Innate Immunity
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	SLAMF6
Full Name	SLAM Family Member 6
Background	The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alternative Names	CD352; KALIb
Gene ID	114836
Uniprot ID	Q96DU3

For Research Use Only.

Human SLAMF6 ELISA Matched Antibody Pair Set [ABP-Q-04-340] (CAT#: ABP-Q-04-340)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview