Name: Human XPNPEP2 ELISA Matched Antibody Pair Set [ABP-Q-04-395]
SKU: ABP-Q-04-395
Price: 1120 USD

Human XPNPEP2 ELISA Matched Antibody Pair Set [ABP-Q-04-395] (CAT#: ABP-Q-04-395)

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Human XPNPEP2 antibody pair set for ELISA useCapture Antibody: rabbit anti-XPNPEP2 monoclonal antibodyDetection Antibody: rabbit anti-XPNPEP2 monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$1,120.00
Antibody Pair Set-Package 2	15 × 96 tests	$2,331.43

Datasheet

MSDS

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Lot Number

Antigen Detail
Target	XPNPEP2
Description	Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution to endothelia and brush border epithelia. APP and XPNPEP2 contain homologous blocks of sequence common to members of the "pita bread-fold" protein family, of which Escherichia coli methionine aminopeptidase is the prototype. The C-2399A variant in XPNPEP2 is associated with reduced APP activity and a higher incidence of AE-ACEi. XPNPEP2 mRNA was detected in fibroblasts that carry the translocation, suggesting that this gene at least partially escapes X inactivation. XPNPEP2 is a candidate gene for premature ovarian failure (POF).
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Rabbit
Clone	IV014
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Rabbit
Conjugation	HRP
Clone	RD10116
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human XPNPEP2 antibody pair set for ELISA use Capture Antibody: rabbit anti-XPNPEP2 monoclonal antibody Detection Antibody: rabbit anti-XPNPEP2 monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human XPNPEP2
Range	10.94-700 pg/mL
Research Area	Metabolism
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	XPNPEP2
Full Name	X-Prolyl Aminopeptidase 2
Background	Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes.
Alternative Names	AEACEI; APP2
Gene ID	7512
Uniprot ID	O43895

For Research Use Only.

Human XPNPEP2 ELISA Matched Antibody Pair Set [ABP-Q-04-395] (CAT#: ABP-Q-04-395)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview