Mouse PIGR ELISA Matched Antibody Pair Set [ABP-Q-04-307] (CAT#: ABP-Q-04-307)

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Mouse PIGR antibody pair set for ELISA use
Capture Antibody: rabbit anti-mouse PIGR monoclonal antibody
Detection Antibody: rabbit anti-mouse PIGR polyclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
Datasheet
MSDS
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Lot Number

Antigen Detail
TargetPIGR
DescriptionPolymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
Species ReactivityMouse

Capture Antibody
Capture ClonalityMonoclonal
Host SpeciesRabbit
CloneIV01239
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody
Det-ClonalityPolyclonal
Host SpeciesRabbit
ConjugationHRP
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product OverviewMouse PIGR antibody pair set for ELISA use
Capture Antibody: rabbit anti-mouse PIGR monoclonal antibody
Detection Antibody: rabbit anti-mouse PIGR polyclonal antibody conjugated to HRP
SpecificityQuantitative determination of Mouse PIGR
Range7.81-500 pg/mL
Research AreaImmunoglobulins
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene SymbolPIGR
Full NamePolymeric Immunoglobulin Receptor
BackgroundThis gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
Alternative NamesHepatocellular Carcinoma-Associated Protein TB6
Gene ID5284
Uniprot IDP01833

For Research Use Only.

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