Mouse S100A1 ELISA Matched Antibody Pair Set [ABP-Q-04-322] (CAT#: ABP-Q-04-322)

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Mouse S100A1 antibody pair set for ELISA useCapture Antibody: rabbit anti-mouse S100A1 monoclonal antibodyDetection Antibody: rabbit anti-mouse S100A1 monoclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
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Lot Number

Antigen Detail

TargetS100A1
DescriptionS100A1 is a Ca2+ binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.
Species ReactivityMouse

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesRabbit
CloneIV01908
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody

Det-ClonalityMonoclonal
Host SpeciesRabbit
ConjugationHRP
CloneRD1017
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property

Product OverviewMouse S100A1 antibody pair set for ELISA use
Capture Antibody: rabbit anti-mouse S100A1 monoclonal antibody
Detection Antibody: rabbit anti-mouse S100A1 monoclonal antibody conjugated to HRP
SpecificityQuantitative determination of Mouse S100A1
Range31.25-2000 pg/mL
Research AreaInnate Immunity
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolS100A1
Full NameS100 calcium-binding protein A1
BackgroundS100A1, also known as S100 calcium binding protein A1, is a protein encoded by the S100A1 gene in humans. S100A1 is highly expressed in myocardium and skeletal muscle, and is located in the Z disk and sarcoplasmic reticulum. S100A1 has been shown to be a promising candidate for gene therapy to treat cardiac tissue after myocardial infarction.
Alternative NamesS100A1; S100; S100-alpha; S100A; S100 calcium-binding protein A1; S100 calcium binding protein A1
Gene ID6271
Uniprot IDP23297

For Research Use Only.

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