Mouse TFPI2 ELISA Matched Antibody Pair Set [ABP-Q-04-354] (CAT#: ABP-Q-04-354)

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Mouse TFPI2 antibody pair set for ELISA useCapture Antibody: rabbit anti-Mouse TFPI2 monoclonal antibodyDetection Antibody: rabbit anti-Mouse TFPI2 polyclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
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Lot Number

Antigen Detail

TargetTFPI2
DescriptionTissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotein consisting of a short amino-terminal region, three tandem Kunitz-type domains and a positively charged carboxy-terminal tail. TFPI2 inhibits plasmin-dependent activation of several metalloproteinases. TFPI2 is highly abundant in the full-term placenta and widely expressed in various adult human tissues, such as the liver, skeletal muscle, heart, kidney, and pancreas. The expression of TFPI2 in tumors is inversely related to an increasing degree of malignancy, which may suggest a role for TFPI2 in the maintenance of tumor stability and inhibition of the growth of neoplasms. TFPI2 inhibits the tissue factor/factor VIIa (TF/VIIa) complex and a wide variety of serine proteinases including plasmin, plasma kallikrein, factor XIa, trypsin, and chymotrypsin. TFPI2 is involved in regulating pericellular proteases implicated in a variety of physiologic and pathologic processes including cancer cell invasion, vascular inflammation, and atherosclerosis. TFPI2 has also been shown to induce apoptosis and inhibit angiogenesis, which may contribute significantly to tumor growth inhibition.
Species ReactivityMouse

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesRabbit
CloneIV01916
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody

Det-ClonalityPolyclonal
Host SpeciesRabbit
ConjugationHRP
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property

Product OverviewMouse TFPI2 antibody pair set for ELISA use
Capture Antibody: rabbit anti-Mouse TFPI2 monoclonal antibody
Detection Antibody: rabbit anti-Mouse TFPI2 polyclonal antibody conjugated to HRP
SpecificityQuantitative determination of Mouse TFPI2
Range7.81-500 pg/mL
Research AreaBlood
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolTFPI2
Full NameTissue factor pathway inhibitor 2
BackgroundTissue factor pathway inhibitor 2 is a protein that in humans is encoded by the TFPI2 gene.
Alternative NamesTFPI2; PP5; REF1; TFPI-2; tissue factor pathway inhibitor 2
Gene ID7980
Uniprot IDP48307

For Research Use Only.

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