Rat B2M ELISA Matched Antibody Pair Set [ABP-Q-04-33] (CAT#: ABP-Q-04-33)

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Rat B2M antibody pair set for ELISA useCapture Antibody: rabbit anti-Rat B2M monoclonal antibodyDetection Antibody: rabbit anti-Rat B2M monoclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
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Antigen Detail

TargetB2M
DescriptionB2M, also known as β2-Microglobulin or CDABP0092, is a component of MHC class I molecules found expression in all nucleated cells (excludes red blood cells). The major function of MHC class I moleculesis is to display fragments of proteins from within the cell to T-cells and cells containing foreign proteins will be attacked. B2M (β2-Microglobulin) is a low molecular weight protein. It was demonstrated that B2M (β2-Microglobulin) was localized in the membranes of nucleated cells and was found to be associated with HL-A antigens. B2M (β2- Microglobulin) is present in free form in various body fluids and as a subunit of histocompatibility antigens on cell surfaces lateral to the α3 chain. Unlike α3, β2 has no transmembrane region. Directly above β2 lies the α1 chain, which itself is lateral to the α2. In the absence of B2M (β2 microglobulin), very limited amounts of MHC class I (classical and non-classical) molecules can be detected on the surface. In the absence of MHC class I, CD8 T cells, a subset of T cells involved in the development of acquired immunity cannot develop. Low levels of B2M (β2 microglobulin) can indicate non-progression of HIV.
Species ReactivityRat

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesRabbit
CloneIV0144
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody

Det-ClonalityMonoclonal
Host SpeciesRabbit
ConjugationHRP
CloneRD10225
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property

Product OverviewRat B2M antibody pair set for ELISA use
Capture Antibody: rabbit anti-Rat B2M monoclonal antibody
Detection Antibody: rabbit anti-Rat B2M monoclonal antibody conjugated to HRP
SpecificityQuantitative determination of Rat B2M
Range2.66-170 pg/mL
Research AreaSerum Proteins
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolB2M
Full NameBeta-2 microglobulin
Backgroundβ2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excludes red blood cells).[5][6] In humans, the β2 microglobulin protein[7] is encoded by the B2M gene.
Alternative NamesB2M; entrez:567; IMD43; beta-2-microglobulin; Β2 microglobulin
Gene ID567
Uniprot IDP61769

For Research Use Only.

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