siRNA, Anti-Human ACTN4, 2'-F(CAT#: SIRGT02047WQ-2F)
The product SIRGT02047WQ-2F is a type of small interfering RNA (siRNA) that targets ACTN4 gene and regulates the expression of gene. The siRNA interferes with the expression of ACTN4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2ʹ-deoxy-2ʹ-fluoro (2'-F) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_001322033.1; NM_004924.5 |
| Alternative Names | ACTININ-4; FSGS; FSGS1 |
| Related Diseases | Focal Segmental Glomerulosclerosis 1, Genetic Steroid-Resistant Nephrotic Syndrome |
| Purification | HPLC |
