siRNA, Anti-Human ACTN4, LNA(CAT#: SIRGT04047WQ-LNA)

The product SIRGT04047WQ-LNA is a type of small interfering RNA (siRNA) that targets ACTN4 gene and regulates the expression of gene. The siRNA interferes with the expression of ACTN4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001322033.1; NM_004924.5
Alternative Names ACTININ-4; FSGS; FSGS1
Related Diseases Focal Segmental Glomerulosclerosis 1, Genetic Steroid-Resistant Nephrotic Syndrome
Purification HPLC
Target Gene
Gene ID 81
Uniprot ID O43707

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