siRNA, Anti-Human APP, 2'-MOE(CAT#: SIRGT03235WQ-2MOE)

The product SIRGT03235WQ-2MOE is a type of small interfering RNA (siRNA) that targets APP gene and regulates the expression of gene. The siRNA interferes with the expression of APP gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2'-O-methoxyethyl (2'-MOE)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_000484.3; NM_001136016.3; NM_001136129.2; NM_001136130.2; NM_001136131.2; NM_001204301.1; NM_001204302.1; NM_001204303.1; NM_201413.2; NM_201414.2
Alternative Names AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4
Related Diseases Cerebral Amyloid Angiopathy, Alzheimer Disease
Purification HPLC
Target Gene
Gene ID 351
Uniprot ID P05067

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