siRNA, Anti-Human APP, LNA(CAT#: SIRGT04235WQ-LNA)
The product SIRGT04235WQ-LNA is a type of small interfering RNA (siRNA) that targets APP gene and regulates the expression of gene. The siRNA interferes with the expression of APP gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | Locked Nucleic Acid (LNA) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_000484.3; NM_001136016.3; NM_001136129.2; NM_001136130.2; NM_001136131.2; NM_001204301.1; NM_001204302.1; NM_001204303.1; NM_201413.2; NM_201414.2 |
| Alternative Names | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 |
| Related Diseases | Cerebral Amyloid Angiopathy, Alzheimer Disease |
| Purification | HPLC |
