This product is a NAMALWA B cell engineering tool based on the Microbubbles (Transferrin/Transferrin receptor) delivery system and CRISPR-based (hROSA26-SpCas9-NLS-Cas9-RS-1 ) genome editor.
| Host Cell | NAMALWA |
| Target | ACTN1 |
| Insert Clone | 10K98 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Microbubbles |
| Ligand/Receptor | Transferrin/Transferrin receptor |
| Active Agents | DOX |
| Particle Size | ≤10000 |
| Charge (mv) | 10 to 100 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Renal cancer; Lung cancer; Head and Neck cancer; Urothelial cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.