ALPP mAb (SP15) Ramos (RA 1) B Cell Engineering Cassette (CAT#: BGS-0124-CR264)

This product is a Ramos (RA 1) B cell engineering tool based on the Nanoparticles (Tumor-homingpeptide tLyp-1/NRP-1) delivery system and CRISPR-based (SHS-317-tracr RNA-Cas9-RS-1 ) genome editor.

Datasheet

Specifications

Host Cell Ramos (RA 1)
Target ALPP
Insert Clone SP15
Safe Harbor Sites (SHS) SHS-317
gRNA tracr RNA
Nuclease Cas9
Enhancer RS-1 (RAD51-stimulatory compound 1)
Targeting Strategy pH-dependent
Insertion sites Large DNA sequences
Vehicles Nanoparticles
Ligand/Receptor Tumor-homing
peptide tLyp-1/NRP-1
Active Agents Paclitaxel, chlorin e6
Particle Size 10-50
Charge (mv) −25 to -125
Total Atom Count ~20,000,000
Surface Atoms (%) ~4
Specific Surface Area (m2/g) ~8
Vector Type Lentivirus
Vector Name BCpCDH2
Targeting Diseases Breast cancer; Lung cancer; Colorectal cancer
COA

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