This product is a HS-Sultan B cell engineering tool based on the Nanoparticles (Transferrin/Transferrin receptor) delivery system and CRISPR-based (huROSA-26-crispr RNA-SpCas9-L755507) genome editor.
| Host Cell | HS-Sultan |
| Target | BST2 |
| Insert Clone | BG-26B |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Transferrin/Transferrin receptor |
| Active Agents | Celastrol |
| Particle Size | 10-1000 |
| Charge (mv) | 10 to 35 |
| Total Atom Count | -22000000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Non-small cell lung cancer; Prostate cancer; Liver cancer |
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