This product is a ST486 B cell engineering tool based on the Solid lipid nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (hROSA26-tracr RNA-Cas9-SCR7 pyrazine ) genome editor.
| Host Cell | ST486 |
| Target | CCL2 |
| Insert Clone | 1.17RT1 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Bortezomib |
| Particle Size | <2500 |
| Charge (mv) | −25 to -47 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.