This product is a Raji-Luc2 B cell engineering tool based on the Solid lipid nanoparticles (EpCAM aptamer/Epithelial cell adhesion molecule) delivery system and CRISPR-based (SHS-229-huIgH296-Cpf1-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Raji-Luc2 |
| Target | CCL2 |
| Insert Clone | BG-62E |
| Safe Harbor Sites (SHS) | SHS-229 |
| gRNA | huIgH296 |
| Nuclease | Cpf1 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | EpCAM aptamer/Epithelial cell adhesion molecule |
| Active Agents | Celastrol |
| Particle Size | 10-1000 |
| Charge (mv) | < 0.5 |
| Total Atom Count | -22,000,000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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