This product is a Ramos (RA 1) B cell engineering tool based on the Micelles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-317-SpCas9-NLS-Cas9-L755507 ) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | CD276 |
| Insert Clone | 8D9 |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Human genome |
| Vehicles | Micelles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | 20-150 |
| Charge (mv) | −25 to -125 |
| Total Atom Count | ~60,000,000 |
| Surface Atoms (%) | ~0.8 |
| Specific Surface Area (m2/g) | ~2.5 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.