CD276 mAb (BG-48E) MC116 B Cell Engineering Cassette (CAT#: BGS-0324-CR543)

This product is a MC116 B cell engineering tool based on the Sphingosomes (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (SHS-255-SpCas9-NLS-Cas9-3'-Azido-3'-deoxythymidine) genome editor.

Datasheet

Specifications

Host Cell MC116
Target CD276
Insert Clone BG-48E
Safe Harbor Sites (SHS) SHS-255
gRNA SpCas9
Nuclease NLS-Cas9
Enhancer 3'-Azido-3'-deoxythymidine
Targeting Strategy Enzyme responsive, time-dependent
Insertion sites Unproductive heavy chain
Vehicles Sphingosomes
Ligand/Receptor SS-Fc/Carcinoembryonic antigen
Active Agents [Ru(bpy)2(tip)]2+, RBT
Particle Size 20-3000
Charge (mv) 10-93
Total Atom Count -64,000,000
Surface Atoms (%) -0.5
Specific Surface Area (m2/g) -0.7
Vector Type MMLV
Vector Name BCpCDH5
Targeting Diseases Ovarian cancer; Breast cancer; Pancreatic cancer
COA

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