This product is a Raji-Luc2 B cell engineering tool based on the Nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (huROSA-26-crispr RNA-SpCas9-L755507) genome editor.
| Host Cell | Raji-Luc2 |
| Target | CD276 |
| Insert Clone | BG-50E |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | Regorafenib |
| Particle Size | 20-3000 |
| Charge (mv) | <80 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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