This product is a Raji-Luc2 B cell engineering tool based on the Niosomes (Anti-EGFR mAb/Epidermal GrowthFactor Receptor) delivery system and CRISPR-based (hROSA26-tracr RNA-Cas9-RS-1 ) genome editor.
| Host Cell | Raji-Luc2 |
| Target | CD7 |
| Insert Clone | 3Ale-12H7 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH-dependent |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Niosomes |
| Ligand/Receptor | EGFR mAb/Epidermal Growth Factor Receptor |
| Active Agents | Thymoquinone |
| Particle Size | 20-3500 |
| Charge (mv) | 10 to 55 |
| Total Atom Count | ~60,000,000 |
| Surface Atoms (%) | ~0.8 |
| Specific Surface Area (m2/g) | ~2.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Pancreatic cancer |
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