This product is a Ramos (RA 1) B cell engineering tool based on the Nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (AAVS1-SpCas9-Cas9-RS-1 ) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | CD7 |
| Insert Clone | PG001 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | SpCas9 |
| Nuclease | Cas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Thymoquinone |
| Particle Size | 10-50 |
| Charge (mv) | 10 to 100 |
| Total Atom Count | ~20,000,000 |
| Surface Atoms (%) | ~4 |
| Specific Surface Area (m2/g) | ~8 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Breast cancer; Lung cancer; Pancreatic cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.