This product is a Ramos (RA 1) B cell engineering tool based on the Sphingosomes (EpCAM aptamer/Epithelial cell adhesion molecule) delivery system and CRISPR-based (CCR5-sgRNA-Cpf1-L755507) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | DENV |
| Insert Clone | HMB-DV5 |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Sphingosomes |
| Ligand/Receptor | EpCAM aptamer/Epithelial cell adhesion molecule |
| Active Agents | Celastrol |
| Particle Size | 41-3500 |
| Charge (mv) | <81 |
| Total Atom Count | -61000000 |
| Surface Atoms (%) | -0.7 |
| Specific Surface Area (m2/g) | -3.6 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Breast cancer; Lung cancer; Brain cancer; Colon cancer; Ovarian cancer |
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