This product is a Raji-Luc2 B cell engineering tool based on the Microbubbles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-317-SpCas9-SpCas9-RS-1) genome editor.
| Host Cell | Raji-Luc2 |
| Target | DENV |
| Insert Clone | F71LQ8 |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | SpCas9 |
| Nuclease | SpCas9 |
| Enhancer | RS-1 |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Microbubbles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | ≤24100 |
| Charge (mv) | −27 to -127 |
| Total Atom Count | -73000000 |
| Surface Atoms (%) | -0.6 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Brain cancer; Colon cancer; Ovarian cancer |
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