This product is a GA-10 (Clone 4) B cell engineering tool based on the Magnetic nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-Nocodazole) genome editor.
| Host Cell | GA-10 (Clone 4) |
| Target | FLT1 |
| Insert Clone | BG-2F |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Magnetic nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | <2300 |
| Charge (mv) | -25 to -125 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Breast cancer; Lung cancer; Colon cancer |
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