This product is a ST486 B cell engineering tool based on the Liposomes (Tumor-homing peptide tLyp-1/NRP-1) delivery system and CRISPR-based (CCR5-tracr RNA-Cas9-Brefeldin A) genome editor.
| Host Cell | ST486 |
| Target | FLT1 |
| Insert Clone | BG-92E |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Mouse genome E-1 |
| Vehicles | Liposomes |
| Ligand/Receptor | Tumor-homing peptide tLyp-1/NRP-1 |
| Active Agents | Thymoquinone |
| Particle Size | ≤10000 |
| Charge (mv) | -10 to -35 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Colon cancer |
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