This product is a Pfeiffer B cell engineering tool based on the Nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-321-tracr RNA-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Pfeiffer |
| Target | FLT1 |
| Insert Clone | BG-8F |
| Safe Harbor Sites (SHS) | SHS-321 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-4 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | ≤10000 |
| Charge (mv) | < 0.5 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Breast cancer; Lung cancer; Colon cancer |
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