GPC3 mAb (GC199) RPMI 1788 B Cell Engineering Cassette (CAT#: BGS-0224-CR858)

This product is a RPMI 1788 B cell engineering tool based on the Liposomes (Folate/ Folate Receptor) delivery system and CRISPR-based (AAVS1-crispr RNA-SpCas9-(Z)-4-Hydroxytamoxifen ) genome editor.

Datasheet

Specifications

Host Cell RPMI 1788
Target GPC3
Insert Clone GC199
Safe Harbor Sites (SHS) AAVS1
gRNA crispr RNA
Nuclease SpCas9
Enhancer (Z)-4-Hydroxytamoxifen
Targeting Strategy pH responsive, mucoadhesiveness
Insertion sites Large DNA sequences
Vehicles Liposomes
Ligand/Receptor Folate/ Folate Receptor
Active Agents Bortezomib
Particle Size <2500
Charge (mv) <80
Total Atom Count ~65,000,000
Surface Atoms (%) ~0.6
Specific Surface Area (m2/g) ~0.8
Vector Type RABV
Vector Name BCpCDH8
Targeting Diseases Breast cancer; Non-small cell lung cancer; Prostate cancer; Liver cancer
COA

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! For Research Use Only | Not For Clinical Use

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