This product is a Farage B cell engineering tool based on the Solid lipid nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (CCR5-sgRNA-Cpf1-RS-1 ) genome editor.
| Host Cell | Farage |
| Target | GPC3 |
| Insert Clone | GC194 |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | RS-1 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Mouse genomeD-4(2) |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Celastrol |
| Particle Size | <2500 |
| Charge (mv) | < 0 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Non-small cell lung cancer; Prostate cancer; Liver cancer |
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