This product is a DS-1 B cell engineering tool based on the Gold nanoparticles (AS1411 aptamer/Nucleolin) delivery system and CRISPR-based (huROSA-26-crRNA:tracrRNA duplex-Cas12-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | DS-1 |
| Target | IL1R1 |
| Insert Clone | BG-6D |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | AS1411 aptamer/Nucleolin |
| Active Agents | Bortezomib |
| Particle Size | <2300 |
| Charge (mv) | <80 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Colon cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.