This product is a DG-75 [D.G.-75] B cell engineering tool based on the Quantum dots (Folate/ Folate Receptor) delivery system and CRISPR-based (AAVS1-SpCas9-Cas12-RS-1) genome editor.
| Host Cell | DG-75 [D.G.-75] |
| Target | KLK1 |
| Insert Clone | BGE6 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | SpCas9 |
| Nuclease | Cas12 |
| Enhancer | RS-1 |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Quantum dots |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | ESC8 |
| Particle Size | 41-150 |
| Charge (mv) | 13 to 67 |
| Total Atom Count | -57000000 |
| Surface Atoms (%) | -0.7 |
| Specific Surface Area (m2/g) | -3.6 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Lung cancer; Prostate cancer; Colorectal cancer |
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