This product is a Ramos (RA 1) B cell engineering tool based on the Nanoparticles (Tumor-homing peptide tLyp-1/NRP-1) delivery system and CRISPR-based (hROSA26-crispr RNA-Cas9-RS-1) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | KLK1 |
| Insert Clone | MQ9T-FQ9 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | crispr RNA |
| Nuclease | Cas9 |
| Enhancer | RS-1 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Tumor-homing peptide tLyp-1/NRP-1 |
| Active Agents | Paclitaxel, chlorin e6 |
| Particle Size | 22-50 |
| Charge (mv) | −31 to -211 |
| Total Atom Count | -23000000 |
| Surface Atoms (%) | -4 |
| Specific Surface Area (m2/g) | -7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Lung cancer; Prostate cancer; Colorectal cancer |
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