This product is a HS-Sultan B cell engineering tool based on the Nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (AAVS1-sgRNA-Cpf1-RS-1) genome editor.
| Host Cell | HS-Sultan |
| Target | LAMA4 |
| Insert Clone | 71L5F7 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | RS-1 |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | DOX |
| Particle Size | 22-500 |
| Charge (mv) | 3 to 21 |
| Total Atom Count | -23000000 |
| Surface Atoms (%) | -4 |
| Specific Surface Area (m2/g) | -7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Colon cancer; Glioblastoma; Gastric cancer; Liver cancer |
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