This product is a Pfeiffer B cell engineering tool based on the Nanoparticles (Anisamide/ Sigma receptors) delivery system and CRISPR-based (AAVS1-huIgH296-Cpf1-Nocodazole) genome editor.
| Host Cell | Pfeiffer |
| Target | NAP1L1 |
| Insert Clone | 2A9-CR |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | huIgH296 |
| Nuclease | Cpf1 |
| Enhancer | Nocodazole |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Mouse genome E-5 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Anisamide/ Sigma receptors |
| Active Agents | Regorafenib |
| Particle Size | 20-2850 |
| Charge (mv) | <-25 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Colorectal cancer; Prostate cancer; Breast cancer |
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