This product is a DS-1 B cell engineering tool based on the Solid lipid nanoparticles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (SHS-323-SpCas9-NLS-Cas9-L755507) genome editor.
| Host Cell | DS-1 |
| Target | SPN |
| Insert Clone | BGC13 |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Human genome |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | 41-150 |
| Charge (mv) | <81 |
| Total Atom Count | -61000000 |
| Surface Atoms (%) | -0.7 |
| Specific Surface Area (m2/g) | -3.6 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Colorectal cancer; Lung cancer |
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