This product is a Pfeiffer B cell engineering tool based on the Solid lipid nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (SHS-317-huIgH296-SpCas9-SCR7 pyrazine) genome editor.
| Host Cell | Pfeiffer |
| Target | SPN |
| Insert Clone | BGC15 |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | huIgH296 |
| Nuclease | SpCas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | Regorafenib |
| Particle Size | 22-2410 |
| Charge (mv) | −2 to -31 |
| Total Atom Count | -23000000 |
| Surface Atoms (%) | -4 |
| Specific Surface Area (m2/g) | -7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Colorectal cancer; Lung cancer |
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