| Overview | |
|---|---|
| Description | This kit is designed for screening inhibitors of PDE4B1 in cultured cells. |
| Features | Ready-used for phoshodiesterase assay. |
| Applications | Screen PDE4B inhibitors for drug discovery & Monitor cAMP/PDE4B signaling pathway activity. |
| Assay Measures | Luminescent |
| Research Areas | Kinase Drug Discovery; Signal Pathway |
| Specification | |
|---|---|
| Size | 500 tests |
| Components | This kit includes a CRE luciferase reporter (premixed with constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency), and a PDE4B1 expression vector. |
| Target | PDE4B |
| Target/Description | Using the assay involves the detection of a fluorescent nucleotide monophosphate generated by PDE3B that binds to a specific binding agent. This assay kit relies on the unique binding agent for precise measurements. With just two simple steps on a microtiter plate, accurate assessment of PDE3B activity can be performed. |
| Format | Luminescent assay kit |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please handle the product at appropriate storage condition once received. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
