Webinar: Improving the Physiological Relevance of Human Brain Organoids

Improving the Physiological Relevance of Human Brain Organoids

Time: 01:00 PM – 02:00 PM EDT, August 5, 2026

Human brain organoids are transforming the study of human brain development and neurodevelopmental disease. However, researchers still face key challenges in generating reproducible, region-specific models that more accurately reflect the physiological complexity of the human brain.

Join Creative Biolabs for an expert-led webinar featuring Giorgia Quadrato, PhD, Associate Professor in the Department of Stem Cell Biology and Regenerative Medicine at the University of Southern California and Director of the USC CIRM ASCEND Shared Resource Laboratory.

In this webinar, Dr. Quadrato will discuss how to improve the physiological relevance of human brain organoids through reproducible region-specific model generation, integration of bioengineering tools, and investigation of cell-type-specific mechanisms in developmental disease.

Why Attend?

Human brain organoids provide a powerful platform for modeling human-specific developmental features and disease mechanisms. Yet their impact depends on how well they capture relevant cellular diversity, regional identity, tissue organization, and physiological context.

This webinar will address how advanced organoid strategies and bioengineering approaches can help improve model reproducibility and physiological relevance. Attendees will gain expert perspectives on how brain organoids can be used to investigate developmental disease mechanisms at cell-type-specific resolution and support more human-relevant 3D biology research.

What You Will Learn

During this webinar, you will gain insights into:

  • How reproducible region-specific brain organoids can be generated for human developmental and disease research
  • How bioengineering tools can be integrated to increase the physiological relevance of brain organoids
  • How human brain organoids can be used to investigate cell-type-specific mechanisms of developmental disease
  • Why regional identity, cellular composition, and model reproducibility are critical for brain organoid applications
  • How single-cell omics and lineage tracing approaches can support deeper mechanistic understanding
  • How advanced 3D biology platforms can contribute to disease modeling, mechanistic discovery, and translational neuroscience research

Who Should Attend?

This webinar is especially relevant for:

  • Researchers studying human brain development, neurodevelopmental disorders, and disease mechanisms
  • Scientists working with human brain organoids, iPSC-derived models, stem cell systems, 3D culture, or tissue engineering
  • Academic and industry teams developing region-specific organoid models for mechanistic or translational studies
  • Pharmaceutical and biotech researchers seeking more physiologically relevant platforms for disease modeling and assay development
  • Scientists interested in integrating bioengineering, single-cell omics, and lineage tracing into organoid-based workflows
  • R&D teams exploring advanced 3D biology models to improve the relevance and predictivity of preclinical research

Featured Speaker

Giorgia Quadrato, PhD

Giorgia Quadrato, PhD

  • Associate Professor
  • Department of Stem Cell Biology and Regenerative Medicine
  • University of Southern California

Director
USC CIRM ASCEND Shared Resource Laboratory

Dr. Giorgia Quadrato is an Associate Professor at USC's Department of Stem Cell Biology and Regenerative Medicine and Director of the USC CIRM ASCEND Shared Resource Laboratory, which provides organoid models, analytical services, consultations, and specialized training.

Her laboratory pioneers human brain organoid models to investigate human-specific developmental features and disease mechanisms in neurodevelopmental disorders. The Quadrato Lab combines brain organoid systems with single-cell omics and bioengineering approaches, including novel lineage tracing systems, to study cellular diversity, developmental trajectories, and disease-relevant mechanisms in human neural tissues.

For research use only. Not for clinical or diagnostic purposes.
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